Optimal Marker-Assisted Selection to Increase the Effective Size of Small Populations

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Optimal marker-assisted selection to increase the effective size of small populations.

An approach to the optimal utilization of marker and pedigree information in minimizing the rates of inbreeding and genetic drift at the average locus of the genome (not just the marked loci) in a small diploid population is proposed, and its efficiency is investigated by stochastic simulations. The approach is based on estimating the expected pedigree of each chromosome by using marker and ind...

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ژورنال

عنوان ژورنال: Genetics

سال: 2001

ISSN: 1943-2631

DOI: 10.1093/genetics/157.2.867